mtDNA
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An A to G point mutation
at position 3243 on the
Mitochondrial DNA
causes MELAS and MIDD.
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A-Z   A B C D E F G H I J K L M N O P Q R S T U V W X Y Z   A-Z

  Carnitine

Fatty Acids are a major source of energy for the body. They are broken down inside mitochondria to produce energy in the form of ATP.

However, fatty acids are unable to cross the inner mitochondrial membrane without the use of Carnitine.

Carnitine is found abundantly in some meat, small amounts in fish, with tiny amounts in fruit and vegetables.

Food mg/100g
Lamb 190
Venison 150
Beef 140
Pork 25
Poultry 13
Fish 3 to 10
Mushrooms 2.5
Banana 0.1
Tomato 0.1

Human adults store about 20 grams of L-Carnitine, primarily in skeletal muscle, in the liver, and in the heart. L-Carnitine is not metabolized or degraded, but excreted in the urine, mostly in the form of Acetyl-L-Carnitine. Therefore, lost L-Carnitine has to be replenished by biosynthesis, by the consumption of foods of animal origin or by consumption of dietary supplements.

See Also
Image of role of Carnitine in transport of fatty acids into mitochondria.
ATP


Author: Andy Collinson. Although I don't have any medical qualifications, as a sufferer of Diabetes, Deafness and Tinnitus caused by the A3243G mtDNA defect, I do have a very keen interest in the subject.

Date Page Updated: 25 April 2005


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