mtDNA
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An A to G point mutation
at position 3243 on the
Mitochondrial DNA
causes MELAS and MIDD.
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- Jargon

A-Z   A B C D E F G H I J K L M N O P Q R S T U V W X Y Z   A-Z

  Ribosome

A Ribosome is a particle inside a cell which manufactures protein.

Briefly, the digital code of how to make a particular protein is stored in DNA inside the nucleus. A copy of this DNA is taken by an mRNA molecule and the mRNA molecule travels out of the nucleus to a Ribosome. The Ribosome then "walks" along the mRNA reading Codons. Each Codon specifies the next Amino Acid to be used when building the protein. The correct amino acid is delivered to the Ribosome by a tRNA. The Ribosome connects that amino acid onto the growing protein, then "walks" onto the next Codon.

A Ribosome is mainly constructed from rRNA.

There are lots of Ribosomes inside a cell to make the proteins which are encoded by the Nuclear DNA.

There are also Ribosomes inside the Mitochondria to make the proteins which are encoded by the mtDNA. The mtDNA also encodes the rRNA to make the Mitochondrial Ribosomes.

See Also
Codon
mRNA
mtDNA
rRNA
tRNA


Author: Andy Collinson. Although I don't have any medical qualifications, as a sufferer of Diabetes, Deafness and Tinnitus caused by the A3243G mtDNA defect, I do have a very keen interest in the subject.

Date Page Updated: 25 April 2005


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